11. In the crossed aldol reaction we perform in 344, an aldehyde reacts with a symmetrical ketone. An example is shown below. O + NaOH EtOH Ph H H3C CH3 Draw the structure of the dehydrated product after 1 mol of benzaldehyde reacts with 1 mol of acetone enolate.
Added by Virginia W.
Close
Step 1
** Show more…
Show all steps
Your feedback will help us improve your experience
Derrick Danso and 66 other Chemistry 101 educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
1. Write the reaction of 2 mols of benzaldehyde with 1 mol of acetone in the presence of sodium hydroxide in ethanol. A. Draw the dehydrated product. B. When performing the cross-aldol reaction, it is very important to control the stoichiometry of the reaction therefore the ketone is added in a drop-wise fashion to a stirring solution of the aldehyde in ethanolic NaOH. Referring to th reaction in #1, draw the product(s) that would form if all the ketone was added to the basic solution at once. Assume the product(s) spontaneously dehydrate.
Hitendra S.
An aldol condensation reaction can take place between two of the same aldehydes or ketones (known as self-condensation) or between two unique aldehydes or ketones (known as crossed aldol condensations). A crossed aldol condensation between acetophenone and pivalaldehyde is shown below. Notice that acetophenone has only one alpha carbon (three acidic hydrogen atoms) whereas pivalaldehyde has no protons on the alpha carbon and can only act as an electrophile in this crossed aldol. In this lab, you will run a crossed aldol reaction using benzaldehyde and acetone. Because acetone has two alpha carbons, it will condense with two molecules of benzaldehyde (one condensation per side), depending on reaction conditions.
Shyam P.
Recommended Textbooks
Chemistry: Structure and Properties
Chemistry The Central Science
Chemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD