Question

1.A small clinic trial was performed to compare the effectiveness of an active drug vs. placebo for relieving symptoms of dry eye. The patients were asked to report their degree of discomfort after 2 weeks. The scale for discomfort includes 0=none, 1=intermittent awareness, 2=constant awareness, 3=intermittent discomfort, 4=constant discomfort. The results are shown in the following table: Active drug Placebo 2 6 2 Ocular discomfort 3 17 13 4 37 44 Total 60 59 a. What test can be used to assess whether the active drug had significant effect on relieving symptom of dry eye? b. Perform the test and report two-tailed p-value and make conclusion.

          1.A small clinic trial was performed to compare the effectiveness of an active drug vs. placebo for relieving symptoms of dry eye. The patients were asked to report their degree of discomfort after 2 weeks. The scale for discomfort includes 0=none, 1=intermittent awareness, 2=constant awareness, 3=intermittent discomfort, 4=constant discomfort. The results are shown in the following table:

Active drug Placebo
2 6 2
Ocular discomfort 3 17 13
4 37 44
Total 60 59

a. What test can be used to assess whether the active drug had significant effect on relieving symptom of dry eye?
b. Perform the test and report two-tailed p-value and make conclusion.

1.A small clinic trial was performed to compare the effectiveness of an active drug vs. placebo for relieving symptoms of dry eye. The patients were asked to report their degree of discomfort after 2 weeks. The scale for discomfort includes 0=none, 1=intermittent awareness, 2=constant awareness, 3=intermittent discomfort, 4=constant discomfort. The results are shown in the following table:

Active drug Placebo
2 6 2
Ocular discomfort 3 17 13
4 37 44
Total 60 59

a. What test can be used to assess whether the active drug had significant effect on relieving symptom of dry eye?
b. Perform the test and report two-tailed p-value and make conclusion.

Added by Andrew C.

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