Question

2 3 4 11 10 5 a C 12 18 17 6 CO₂Me b 4 CO₂Me 09 05 11 10 13 10 125 19 141 15 CO2H 08 d NH 02 2N3 6 7 N. R H -N H R e 0 0 f 12 11 11 10 15 0-14 8 13 5 13 6 Hax вхо 10 7 16 17 FO 9 15 14 02 2N3 F08 Hendo O2N3 8 9 N R N R H H 7 Scheme 2. Synthetic route to N-benzamido imides 7: a) KOH, MeOH, H₂O, reflux, 5 h; then HCl; b) acetic anhydride, reflux, 1 h, 85% yield; c) NH₂NHCOR, diisopropylethylamine, EtOH, reflux, 6 h; d) toluene or xylene, reflux, 24 h; e) dimethyldioxirane, acetone, RT; f) H₂, Pd/C, 1 atm, EtOH.

Name: 2 3 4 11 10 5 a c 12 18 17 6 co2me b 4 co2me 09 05 11 10 13 10 125 19 141 15 co2h 08 d nh 02 2n3 6 7 n r h n h r e 0 0 f 12 11 11 10 15 0 14 8 13 5 13 6 hax 10 7 16 17 fo 9 15 14 02 2n3 f08 60589
Uploaded: 2022-05-13T16:05:02-08:00
Duration: 3 min 42 s
Channel: Shaiju T
Description: 2 3 4 11 10 5 a c 12 18 17 6 co2me b 4 co2me 09 05 11 10 13 10 125 19 141 15 co2h 08 d nh 02 2n3 6 7 n r h n h r e 0 0 f 12 11 11 10 15 0 14 8 13 5 13 6 hax 10 7 16 17 fo 9 15 14 02 2n3 f08 60589

          2
3
4
11
10
5
a
C
12
18
17
6
CO₂Me
b
4 CO₂Me
09
05
11 10
13
10
125
19
141 15
CO2H
08
d
NH
02
2N3
6
7
N.
R
H
-N
H
R
e
0
0
f
12 11
11
10
15
0-14
8
13 5
13
6
Hax
вхо
10
7
16 17
FO 9
15
14
02
2N3
F08 Hendo
O2N3
8
9
N
R
N
R
H
H
7
Scheme 2. Synthetic route to N-benzamido imides 7: a) KOH, MeOH, H₂O,
reflux, 5 h; then HCl; b) acetic anhydride, reflux, 1 h, 85% yield;
c) NH₂NHCOR, diisopropylethylamine, EtOH, reflux, 6 h; d) toluene or xylene,
reflux, 24 h; e) dimethyldioxirane, acetone, RT; f) H₂, Pd/C, 1 atm, EtOH.

2 3 4 11 10 5 a c 12 18 17 6 co2me b 4 co2me 09 05 11 10 13 10 125 19 141 15 co2h 08 d nh 02 2n3 6 7 n r h n h r e 0 0 f 12 11 11 10 15 0 14 8 13 5 13 6 hax 10 7 16 17 fo 9 15 14 02 2n3 f08 60589

Added by Miriam C.

Chemistry: Structure and Properties

Nivaldo Tro 2nd Edition

Instant Answer

Solved by Expert Shaiju T

05/13/2022

Step 1

The scheme starts with compound 4 and proceeds through several steps (a-f) to yield compounds 5, 6, 7, 8, and 9. The reagents and conditions for each step are provided below the scheme. a) KOH, MeOH, H₂O, reflux, 5 h; then HCl b) acetic anhydride, reflux, 1 h, 85% Show more…

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2 3 4 11 10 5 a C 12 18 17 6 CO₂Me b 4 CO₂Me 09 05 11 10 13 10 125 19 141 15 CO2H 08 d NH 02 2N3 6 7 N. R H -N H R e 0 0 f 12 11 11 10 15 0-14 8 13 5 13 6 Hax вхо 10 7 16 17 FO 9 15 14 02 2N3 F08 Hendo O2N3 8 9 N R N R H H 7 Scheme 2. Synthetic route to N-benzamido imides 7: a) KOH, MeOH, H₂O, reflux, 5 h; then HCl; b) acetic anhydride, reflux, 1 h, 85% yield; c) NH₂NHCOR, diisopropylethylamine, EtOH, reflux, 6 h; d) toluene or xylene, reflux, 24 h; e) dimethyldioxirane, acetone, RT; f) H₂, Pd/C, 1 atm, EtOH.