Question

2) Which set of reaction conditions will produce the indicated product? OH -> CN A. 1. TsCl/pyridine 2. NaCN B. PBr3/pyridine 2. NaCN C. SOCl2/pyridine 2. NaCN D. PCl3/pyridine 2. NaCN E. B, C, and D will all work.

          2) Which set of reaction conditions will produce the indicated product?
OH -> CN

A. 1. TsCl/pyridine 2. NaCN
B. PBr3/pyridine 2. NaCN
C. SOCl2/pyridine 2. NaCN
D. PCl3/pyridine 2. NaCN
E. B, C, and D will all work.

Added by Francisca M.

Chemistry: Structure and Properties

Nivaldo Tro 2nd Edition

Instant Answer

Solved by Expert Supreeta N

04/08/2023

Step 1

First, we need to convert the OH group to a better leaving group. This can be done using either TsCl/pyridine (A), PBr3/pyridine (B), SOCl2/pyridine (C), or PCl5/pyridine (D). All of these reagents will replace the OH group with a halogen (OTs, Br, Cl, or Cl, Show more…

Show all steps

Thanks for your feedback!

Which set of reaction conditions will produce the indicated product? A. 1. TsCl/pyridine 2. NaCN B. PBr3/pyridine 2. NaCN C. SOCl2/pyridine 2. NaCN D. PCl3/pyridine 2. NaCN E. B, C, and D will all work.