Question

7. An enzyme with histidine residues that participate in both general acid and general base catalysis would be most likely to have a pH-activity profile resembling which curve? Explain your choice. activity D E B A C 1 2 3 4 5 6 7 8 9 10 11 12 13 14 pH 8. Although enzyme catalysis is reversible, a given reaction may appear irreversible in which of the following situations? Explain your answers (this is not a multiple choice question; analyze each situation to determine if the reaction may appear irreversible under these conditions). a) The products are thermodynamically far more stable than the reactants. b) Under initial velocity conditions. c) If a product is rapidly removed from the system. d) At high enzyme concentrations.

          7. An enzyme with histidine residues that participate in both general acid and general base catalysis would be most likely to have a pH-activity profile resembling which curve?
Explain your choice.
activity
D
E
B
A
C
1 2 3 4 5 6 7 8 9 10 11 12 13 14
pH
8. Although enzyme catalysis is reversible, a given reaction may appear irreversible in which of the following situations? Explain your answers (this is not a multiple choice question; analyze each situation to determine if the reaction may appear irreversible under these conditions).
a) The products are thermodynamically far more stable than the reactants.
b) Under initial velocity conditions.
c) If a product is rapidly removed from the system.
d) At high enzyme concentrations.

Added by Christopher M.

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