Question

A clinical trial is being planned to compare an experimental medication designed to lower blood pressure compared to a placebo. Before starting the trial, a pilot study is conducted with 7 participants to assess how systolic blood pressure changes over time if untreated. Systolic blood pressures are measured at baseline and again 4 weeks later among each of the 7 participants. The data are shown below: Participant 001 002 003 004 005 006 007 Baseline 120 145 130 160 152 143 126 4 Weeks 122 142 135 158 155 140 130 What is an appropriate statistical test to assess if there is a change over time? Select one: a. 2-sample t-test b. Paired t-test c. ANOVA d. Linear regression

          A clinical trial is being planned to compare an experimental medication designed to lower blood pressure compared to a placebo. Before starting the trial, a pilot study is conducted with 7 participants to assess how systolic blood pressure changes over time if untreated. Systolic blood pressures are measured at baseline and again 4 weeks later among each of the 7 participants. The data are shown below:

Participant     001      
002       003      
004       005      
006       007
Baseline         120      
145       130       160    
  152       143      
126     
4 Weeks         122       142
      135       158    
  155       140       130

What is an appropriate statistical test to assess if there is a change over time?
Select one:
a. 2-sample t-test
b. Paired t-test
c. ANOVA
d. Linear regression

Added by Roberto B.

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