A longitudinal study was conducted to examine the effects of a new blood pressure medication for patients with hypertension (high blood pressure). The 155 participants would take the new medication daily and have their blood pressure measured at the end of each week, for 52 weeks. It was hypothesised that blood pressure would be lower at the end of the study compared to the start of the study.
Which of the following would be an appropriate statistical test to conduct, which addresses these hypotheses?