all amino acids have two ionizable functional groups an amino group average pka of 94 and an car

Step 1: Calculate the isoelectric point (pI) of cysteine using the formula pI = (pKa1 + pKa2) /

Question

All amino acids have two ionizable functional groups: an Î±-amino group (average pKa of 9.4) and an Î±-carboxylic acid group (average pKa of 2.2). Cysteine has an ionizable side chain (R group) with a pKa of about 8.3. At what pH would the structure be the predominant ionization state? Consider the ionization state of all three of the functional groups. (4.8, 8.9, 8.3, 11.9, 1.5, or 7.0) The protonated form of the R group of cysteine is shown in the structure. The ratio of the protonated form to the charged (deprotonated) form depends on the pKa of the R group and the pH of the solution. Select all the pH values at which the charged form of the R group would predominate. (9.8, 10.8, 8.3, 5.8)

          All amino acids have two ionizable functional groups: an Î±-amino group (average pKa of 9.4) and an Î±-carboxylic acid group (average pKa of 2.2). Cysteine has an ionizable side chain (R group) with a pKa of about 8.3. 
At what pH would the structure be the predominant ionization state? Consider the ionization state of all three of the functional groups. (4.8, 8.9, 8.3, 11.9, 1.5, or 7.0)
The protonated form of the R group of cysteine is shown in the structure. The ratio of the protonated form to the charged (deprotonated) form depends on the pKa of the R group and the pH of the solution. Select all the pH values at which the charged form of the R group would predominate. (9.8, 10.8, 8.3, 5.8)

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