Question

Ammonia reacts with acetyl chloride $\left(\mathrm{CH}_{3} \mathrm{COCl}\right)$ to give acetamide $\left(\mathrm{CH}_{3} \mathrm{CONH}_{2}\right)$. Identify the bonds broken and formed in each step of the reaction, and draw curved arrows to represent the flow of electrons in each step.

Name: Ammonia reacts with acetyl chloride (CH3COCl) to give acetamide (CH3CONH2). Identify the bonds broken and formed in each step of the reaction, and draw curved arrows to represent the flow of electrons in each step.
Uploaded: 2024-07-02T14:40:28-08:00
Duration: 1 min 59 s
Channel: Narayan Hari
Description: Ammonia reacts with acetyl chloride (CH3COCl) to give acetamide (CH3CONH2). Identify the bonds broken and formed in each step of the reaction, and draw curved arrows to represent the flow of electrons in each step.

          Ammonia reacts with acetyl chloride $\left(\mathrm{CH}_{3} \mathrm{COCl}\right)$ to give acetamide $\left(\mathrm{CH}_{3} \mathrm{CONH}_{2}\right)$. Identify the bonds broken and formed in each step of the reaction, and draw curved arrows to represent the flow of electrons in each step.

Added by Jay A.

Organic Chemistry

Janice Gorzynski Smith 4th Edition

Instant Answer

Solved by Expert Narayan Hari

07/02/2024

Step 1

Step 1: Nucleophilic attack of ammonia on acetyl chloride Bonds broken: $\mathrm{C-O}$ bond in acetyl chloride Bonds formed: $\mathrm{C-N}$ bond between acetyl group and ammonia Electron flow: Lone pair on nitrogen in ammonia attacks the carbonyl carbon in acetyl Show more…

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Ammonia reacts with acetyl chloride $\left(\mathrm{CH}_{3} \mathrm{COCl}\right)$ to give acetamide $\left(\mathrm{CH}_{3} \mathrm{CONH}_{2}\right)$. Identify the bonds broken and formed in each step of the reaction, and draw curved arrows to represent the flow of electrons in each step.