00:01
Hello everyone, in this question it is said that the psychoactive drugs have their action at or near the synapse.
00:11
So we need to describe four possible mechanisms by which these drugs can have their effect.
00:17
So there are two types of the drugs, the agonistic and the antagonistic.
00:25
So the agonistic drug facilitates the effect of the neurotransmitter and the antagonistic inhibit the particular neurotransmitter.
00:37
So the effect here can be that one class of drug increases the synthesis of neurotransmitters.
00:51
Molecule like there is l -dopa is the precursor of the catecholamine as well as the dopamine.
01:01
So if we increase the level of the l -dopa here in the nervous system, it will often result in an increased activity of the dopamine and the drug is used to treat a movement disorder that is known as the parkinson's disease.
01:20
Then lecithin is also there which is the precursor of the acetylcholine.
01:27
It is sometimes used to cure the alzheimer's disease.
01:34
The more complicated mechanism affects the synthesis of the neurotransmitter and it involves the inhibition of the auto -receptors that is located on the neurons ' dendrites.
01:45
Then another effect of neurotransmitter is the enzymatic breakdown...