Answer the following questions about ether synthesis and cleavage.
a. Provide a detailed mechanism for the following two ether synthesis reactions. Note the differences in reagents and consider the impact of the acidic vs basic conditions.
b. Compare and contrast the two pathways above. Which would you expect to be the better/faster reaction? Why?
c. Provide a detailed mechanism for the following two ether cleavage reactions. Note the differences in reagents and consider the impact of the acidic vs basic conditions.
d. Compare and contrast the two pathways above. Which would you expect to be the better/faster reaction? Why?
2
Answer the following guestions about ether synthesis and cleavage
a.
Provide a detailed mechanism for the following two ether synthesis reactions.Note the differences in reagents and consider the impact of the acidic vs basic conditions
NaOH (xs)
2
H2O
M
Me
Br
H2O
HO
+
b. Compare and contrast the two pathways above.Which would you expect to be the better/faster reaction?Why?
C. Provide a detailed mechanism for the following two ether cleavage reactions. Note the differences in reagents and consider the impact of the acidic vs basic conditions
NaOH
Me
H2O
Me
OF
HBr (xs)
Me
HO
d. Compare and contrast the two pathways above.Which would you expect to be the better/faster reaction?Why?