Question

Antibody & Immunohistochemical Methods In a study of the proliferative activity of breast cancers, Veronese and Gambacorta (A-1) used the Ki-67 monoclonal antibody and Immunohistochemical methods. The investigators obtained tumor tissues from 203 patients with breast carcinoma. The patients ranged in age from 26-82 years. The following table shows the Ki-67 values (expressed as percentages) for these patients. 10.12 10.80 10.54 27.30 8.38 10.15 5.48 23.50 32.60 42.70 19.30 16.40 4.40 26.80 16.60 9.63 9.31 7.40 1.73 35.90 33.00 11.65 26.30 9.35 14.78 21.42 25.11 12.60 17.96 41.12 28.30 19.50 15.92 19.40 7.19 4.65 73.00 17.84 10.90 2.74 21.09 11.95 33.30 4.53 19.40 1.00 27.00 9.03 51.20 6.40 13.72 32.90 9.80 2.43 2.00 8.77 9.40 35.40 51.70 43.50 3.00 4.70 14.00 15.00 3.60 4.09 9.20 6.20 5.00 15.00 17.60 50.00 10.00 20.00 30.00 5.22 5.00 15.00 25.00 10.00 12.70 30.00 10.00 15.00 20.00 7.39 4.00 25.00 20.00 30.00 21.36 49.85 29.70 19.95 5.00 11.36 24.89 29.55 10.00 38.90 8.12 28.85 19.80 4.99 6.00 3.14 5.00 44.20 30.00 9.88 4.33 9.20 4.87 10.00 29.10 5.07 2.00 3.00 2.00 2.96 8.10 4.84 9.79 5.00 9.50 4.23 10.00 19.83 20.00 4.77 13.11 75.00 20.00 5.00 4.55 4.07 14.79 8.99 3.97 30.00 6.07 15.00 40.00 18.79 13.76 45.82 4.32 5.69 1.42 18.57 5.58 12.82 4.50 4.41 1.88 5.00 10.00 4.12 14.24 9.11 9.69 8.37 6.20 2.07 3.12 4.14 2.03 2.69 3.69 5.42 4.59 10.00 6.27 6.37 13.78 27.55 9.83 6.55 8.21 3.42 3.51 9.10 11.20 6.88 7.53 8.58 5.00 29.50 9.60 6.03 14.70 5.60 28.10 5.48 7.00 6.72 3.32 13.52 5.70 17.80 13.10 9.75 7.37 SOURCE: Silvio M. Veronese, Ph.D. Used with permission (b) What percentage of the measurements are less than 10? (a) Use these data to prepare: A frequency distribution (c) What proportion of the subjects have measurements greater than or equal to 20? A relative frequency distribution (d) What percentage of the measurements are between 20 and 49 inclusive? A cumulative frequency distribution (e) How many of the measurements are greater than 39? Cumulative relative frequency distribution (f) What proportion of the measurements are either less than 10 or greater than 69? A histogram A frequency polygon (g) Someone picks a measurement at random from this data set and asks you to guess the value. What would be your answer? Why?

          Antibody & Immunohistochemical Methods
In a study of the proliferative activity of breast cancers, Veronese and Gambacorta (A-1) used the Ki-67 monoclonal antibody and
Immunohistochemical methods. The investigators obtained tumor tissues from 203 patients with breast carcinoma. The patients
ranged in age from 26-82 years. The following table shows the Ki-67 values (expressed as percentages) for these patients.
10.12 10.80 10.54 27.30 8.38
10.15 5.48 23.50 32.60 42.70
19.30 16.40 4.40 26.80 16.60
9.63 9.31 7.40 1.73 35.90
33.00 11.65 26.30 9.35 14.78
21.42 25.11 12.60 17.96 41.12
28.30 19.50 15.92 19.40 7.19
4.65 73.00 17.84 10.90 2.74
21.09 11.95 33.30 4.53 19.40
1.00 27.00 9.03 51.20 6.40
13.72 32.90 9.80 2.43 2.00
8.77 9.40 35.40 51.70 43.50
3.00 4.70 14.00 15.00 3.60
4.09 9.20 6.20 5.00 15.00
17.60 50.00 10.00 20.00 30.00
5.22 5.00 15.00 25.00 10.00
12.70 30.00 10.00 15.00 20.00
7.39 4.00 25.00 20.00 30.00
21.36 49.85 29.70 19.95 5.00
11.36 24.89 29.55 10.00 38.90
8.12 28.85 19.80 4.99 6.00
3.14 5.00 44.20 30.00 9.88
4.33 9.20 4.87 10.00 29.10
5.07 2.00 3.00 2.00 2.96
8.10 4.84 9.79 5.00 9.50
4.23 10.00 19.83 20.00 4.77
13.11 75.00 20.00 5.00 4.55
4.07 14.79 8.99 3.97 30.00
6.07 15.00 40.00 18.79 13.76
45.82 4.32 5.69 1.42 18.57
5.58 12.82 4.50 4.41 1.88
5.00 10.00 4.12 14.24 9.11
9.69 8.37 6.20 2.07 3.12
4.14 2.03 2.69 3.69 5.42
4.59 10.00 6.27 6.37 13.78
27.55 9.83 6.55 8.21 3.42
3.51 9.10 11.20 6.88 7.53
8.58 5.00 29.50 9.60 6.03
14.70 5.60 28.10 5.48 7.00
6.72 3.32 13.52 5.70 17.80
13.10 9.75 7.37
SOURCE: Silvio M. Veronese, Ph.D. Used with permission
(b) What percentage of the measurements are less than 10?
(a) Use these data to prepare:
A frequency distribution
(c) What proportion of the subjects have measurements greater than or equal to 20?
A relative frequency distribution
(d) What percentage of the measurements are between 20 and 49 inclusive?
A cumulative frequency distribution
(e) How many of the measurements are greater than 39?
Cumulative relative frequency distribution (f) What proportion of the measurements are either less than 10 or greater than 69?
A histogram
A frequency polygon
(g) Someone picks a measurement at random from this data set and asks you to
guess the value. What would be your answer? Why?

antibody immunohistochemical methods in a study of the proliferative activity of breast cancers veronese and gambacorta a 1 used the ki 67 monoclonal antibody and immunohistochemical methods 70437

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