code class="asciimath">The equivalent weight of aspirin is 90 (i.e.( 180)/(2)=90). Hence each milliliter of 0.5N NaOH is equivalent to 45mg of aspirin.
Added by Patricia S.
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The equivalent weight of a substance is the mass of that substance that will react with or replace one mole of hydrogen ions (Hāŗ) in a reaction. For aspirin, the equivalent weight is given as 90 mg. Show moreā¦
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Acetylsalicylic acid is (MW 180.159 g/mol) is a weak monoprotic acid (HA, pKa = 3.5), that is commonly known as the drug "aspirin". One aspirin tablet is crushed and dissolved in 100.00 mL of DI water in a beaker. The solution is then titrated with 0.1671 M NaOH as titrant. If 18.62 mL of NaOH is used to reach the endpoint, using phenolphthalein as indicator, calculate the mass of aspirin in one tablet in milligrams (mg). Express your answer with two decimal places.
Adi S.
We will titrate aspirin (acetylsalicylic acid: HC9H7O4 FW 180.159 g) in a tablet. We expect about 320 mg of aspirin in the tablet. Aspirin is a monoprotic weak acid. What concentration of NaOH titrant is needed for this sample if we want a titration equivalence volume of about 12 mL?
David C.
Acetylsalicylic acid (HC, H $_{7} \mathrm{O}_{4}$ ) is a monoprotic acid commonly known as "aspirin." A typical aspirin tablet, however, contains only a small amount of the acid. In an experiment to determine its composition, an aspirin tablet was crushed and dissolved in water. It took $12.25 \mathrm{mL}$ of $0.1466 \mathrm{M} \mathrm{NaOH}$ to neutralize the solution. Calculate the number of grains of aspirin in the tablet (one grain $=0.0648 \mathrm{g}$ ).
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