Denaturation and Hydrolysis
Simply put, denaturation means unfolding. Previous pages have discussed the factors that stabilize the shape of a protein, with all its helices, loops, and folds. If those stabilizing factors are disrupted, the protein falls out of shape. Even though its amino acids (primary structure) remain linked, without its correct secondary and tertiary structure the denatured protein can no longer function. For example, the body's enzymes lose their ability to catalyze the needed chemical reactions, if our body temperature changes too drastically. (Denatured proteins sometimes taste better though! People who eat eggs often prefer them cooked – denatured by heat. In ceviche, the seafood proteins are "cooked" by denaturing them with lime juice, which is acidic.)
List the six causes of protein denaturation: