CHEM3412 Lab Synthesis of 1,4-Di-t-butyl-2,5-dimethoxybenzene by Friedel-Crafts Alkylation OCH$_3$ OCH$_3$ OCH$_3$ OH + 2 $H_3C\overset{\cdot}{C}(CH_3)_2$ + 2H$_2$O OCH$_3$
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The first step is the formation of the electrophile, which is t-butyl cation (t-Bu+). This is achieved by the reaction of t-butyl chloride (t-BuCl) with aluminum chloride (AlCl3) as a Lewis acid catalyst. t-BuCl + AlCl3 → t-Bu+ + AlCl4- Show more…
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