Question

Electrophilic aromatic substitution reactions of pyridine normally occur at C3. Draw the carbocation intermediates resulting from electrophilic attack at C1, C2, and C3, and explain the observed result.

Name: Electrophilic aromatic substitution reactions of pyridine normally occur at C3. Draw the carbocation intermediates resulting from electrophilic attack at C1, C2, and C3, and explain the observed result.
Uploaded: 2021-12-24T02:22:35-08:00
Duration: 1 min 58 s
Channel: Grigoriy Sereda
Description: Electrophilic aromatic substitution reactions of pyridine normally occur at C3. Draw the carbocation intermediates resulting from electrophilic attack at C1, C2, and C3, and explain the observed result.

          Electrophilic aromatic substitution reactions of pyridine normally occur at C3. Draw the carbocation intermediates resulting from electrophilic attack at C1, C2, and C3, and explain the observed result.

Added by Jacob R.

Organic Chemistry

Janice Gorzynski Smith 4th Edition

Instant Answer

Solved by Expert Grigoriy Sereda

12/24/2021

Step 1

The positive charge is localized on the carbon at C1, leading to a less stable intermediate due to the nitrogen's higher electronegativity compared to carbon. ** Show more…

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Electrophilic aromatic substitution reactions of pyridine normally occur at C3. Draw the carbocation intermediates resulting from electrophilic attack at C1, C2, and C3, and explain the observed result.