Experiment 4: Synthesis of Ethyl Acetate
Techniques/Topics: esterification (synthesis), gas chromatography
Read: Technique 8
Background:
Esters are an important class of organic compounds, which often have a pleasant smell and therefore are components of many natural fragrances. Esters can be synthetically prepared for use in foods, flavorings, and perfumes utilizing a condensation reaction known as a Fischer esterification. A condensation reaction is one in which a molecule of water is created as a byproduct. This water comes from the starting components of an alcohol and an acid, often a carboxylic acid. A catalyst, such as concentrated acid, is added to accelerate the reaction. However, this reaction does not create a high yield of products, but has an equilibrium only slightly favoring product formation, often with a K of 4-10. If more product formation is desired, according to Le Chatelier's Principle, either product would need to be removed or more reactants added.
Sample esterifications:
Alcohol
Acid
Ester
Odor