For the SN2 mechanism that you will be performing in class the 2-naphthol is premixed with NaOH and refluxed before the addition of bromobutane. What is the purpose of premixing the 2-naphthol with the NaOH?
(Multiple Answer: Multiple answers may be correct, and all correct answers must be indicated for full credit)
For the SN2 mechanism that you will be performing in class the 2-naphthol is premixed with NaOH and refluxed before the addition of bromobutane. What is the purpose of premixing the 2-naphthol with the NaOH?
(Multiple Answer: Multiple answers may be correct, and all correct answers must be indicated for full credit)
NaOH will remove the proton from 2-naphthol creating a strong nucleophile which is necessary for an SN2 reaction.
NaOH will remove the proton from 2-naphthol creating a primary substrate which is favors an SN2 reaction.
NaOH will donate a proton to 2-naphthol creating a strong nucleophile which is necessary for an SN2 reaction.
NaOH will donate a proton to 2-naphthol creating a primary substrate which favors for an SN2 reaction.
NaOH is a solvent for the reaction and does not participate in the mechanism.