Question

Genetic influences on cancer can be studied by manipulating the genetic makeup of mice. One of the processes that turn genes on or off (so to speak) in particular locations is called "DNA methylation." Do low levels of this process help cause tumors? Compare mice altered to have low levels with normal mice. Of the 33 mice with lowered levels of DNA methylation, 23 developed tumors. None of the control group of 18 normal mice developed tumors in the same time period. Step 1: The plus four method adds two observations, a success and a failure, to each sample. What are the sample sizes and the numbers of mice with tumors after you do this? After adding the two observations to each sample size, the sample size for the treatment group is Answer 1, Answer 2 of which have tumors. The sample size for the control group is Answer 3, Answer 4, of which has a tumor. Answer 1: Answer 2: Answer 3: Answer 4: Step 2: Give a 99% confidence interval for the difference in the proportions of the two populations that develop tumors. (Round your answers to 4 decimal places.) Answer 1 to Answer 2 Answer 1: Answer 2:

          Genetic influences on cancer can be studied by manipulating the genetic makeup of mice. One of the processes that turn genes on or off (so to speak) in particular locations is called "DNA methylation." Do low levels of this process help cause tumors? Compare mice altered to have low levels with normal mice. Of the 33 mice with lowered levels of DNA methylation, 23 developed tumors. None of the control group of 18 normal mice developed tumors in the same time period.

Step 1: The plus four method adds two observations, a success and a failure, to each sample. What are the sample sizes and the numbers of mice with tumors after you do this? After adding the two observations to each sample size, the sample size for the treatment group is __Answer 1__, __Answer 2__ of which have tumors. The sample size for the control group is __Answer 3__, __Answer 4__, of which has a tumor.

Answer 1: 
Answer 2: 
Answer 3: 
Answer 4: 

Step 2: Give a 99% confidence interval for the difference in the proportions of the two populations that develop tumors. (Round your answers to 4 decimal places.) __Answer 1__ to __Answer 2__

Answer 1: 
Answer 2:

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