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Hello students, in the following case study we have been asked various questions based on it.
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The first one is, do the lab data support a diagnosis of the disorder hemostasis? so to answer this, yes, the lab data does suggest or support a diagnosis of the hemostasis.
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The second question is, the prolonged ptt, that is 60 seconds, which is higher than the normal range, which is about 28 to 35 seconds, that indicates a potential issue with the intrinsic or common coagulation pathway.
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If you talk about the second question, which disorder is to be suspected about? so based on the prolonged ptt, appt and the family history of a bleeding problem, a coagulation factor deficiency such as hemophilia a, that is factor viii deficiency or hemophilia b, that is factor ix deficiency can be suspected.
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Third question is about the types of disorders can be preliminary identified by the tests that were performed.
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So the types, the tests performed can help identify disorders related to coagulation factors, platelets function and fibrinogen levels.
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In this case a prolonged appt suggests that a potential effect on intrinsic and common coagulation pathway is there.
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Next is the fourth question, what is mixing test and how relevant will it be for this patient's diagnosis? so a mixing test is a lab procedure used to differentiate between factors deficiency and the presence of inhibitors such as between factor deficiency and the presence of inhibitor, for example, an antibody that interferes with coagulation.
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It involves mixing the patient's plasma with normal plasma and then measuring the coagulation.
03:23
If the coagulation time is correct to normal, it suggests a factor deficiency...