Hyperuricemia. Many patients with glucose 6 -phosphatase deficiency have high serum levels of urate. Hyperuricemia can be induced in normal people by the ingestion of alcohol or by strenuous exercise. Propose a common mechanism that accounts for these findings.
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Step 1: Patients with glucose 6-phosphatase deficiency have high serum levels of urate because of the decreased cytoplasmic level of ATP in their liver, leading to increased purine breakdown. Show more…
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