00:01
Hello everyone, so here our question is antibiotics, antibiotics can kill the gram negative bacteria, kills the gram negative bacteria but symptoms of fever and low blood pressure can persist.
00:25
Why? this is our question.
00:28
So this gram negative bacteria produces or they have this protective layer, protective outer layer which is made up of a substance called a lipopolysaccharide, that is the lipopolysaccharides.
00:54
So when the bacteria are killed by the antibiotics they release, bacteria will release their, release their outer layer, outer layer called the lps that is lipopolysaccharide.
01:18
So this lipopolysaccharide is recognized by our immune system which is recognized by our immune system, our immune system as a danger signal triggering a strong response.
01:41
So this lps is recognized by our immune system and they respond by releasing a substance called cytokine, cytokine.
01:56
So this immune system release the cytokine as a result of this or as a response to this lipopolysaccharide.
02:08
So this cytokines help to fight off the infection but they can also cause, they can also cause the inflammation, inflammation throughout the body, throughout the body...