Is proton on or off R group at pH = 7.4 for Aspartate? O On O Off
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The pKa of the R group of aspartate is approximately 3.9. Show more…
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A solution of the amino acid Aspartic Acid is at pH 1. What will be the overall charge, the charge on the two functional groups, and the R group? Aspartic Acid has a pl of 2.77 A) The side groups will be -COO- and -NH3+. The R group will be -COO- . Overall the charge will be -1. B) The side groups will be -COOH and -NH3+. The R group will be -COOH. Overall the charge will be +1. C)The side groups will be -COOH and -NH2. The R group will be -COOH. Overall the charge will be neutral. D) The side groups will be -COO- and -NH2. The R group will be -COO- . Overall the charge will be -2. E) The side groups will be -COO- and -NH3+.
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A solution of the amino acid Aspartic Acid is at pH 13. What will be the overall charge, the charge on the two functional groups, and the R group? Aspartic Acid has a pI of 2.77. A) The side groups will be -COO- and -NH3+. The R group will be -COO-. Overall the charge will be -1. B) The side groups will be -COOH and -NH3+. The R group will be -COO-. Overall the charge will be neutral. C) The side groups will be -COOH and -NH2. The R group will be -COOH. Overall the charge will be neutral. D) The side groups will be -COO- and -NH2. The R group will be -COO-. Overall the charge will be -2. E) The side groups will be -COO- and -NH3+. The R group will be -COOH. Overall the charge will be -1.
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The pK1, pK2, and pKR for the amino acid aspartic acid are 2.0, 9.9, and 3.9, respectively. At pH 7.0, aspartic acid would be charged predominantly as follows: a) a-carboxylate 0, a-amino +1, b-carboxylate 0, net charge +1 b) a-carboxylate -1, a-amino +1, b-carboxylate -1, net charge -1 c) a-carboxylate 0, a-amino -1, b-carboxylate 0, net charge -1 d) a-carboxylate +1, a-amino +1, b-carboxylate +1, net charge +3
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