Leucine has two dissociable protons: one with a pK$_a$ of 2.3, the other with a pK$_a$ of 9.7. Indicate full pH regions at which it can act as a buffer 1.3-2.3 and 8.7-9.7 2.3-3.3 and 9.7-10.7 1.3-3.3 and 8.7-10.7
Added by Michelle T.
Close
Step 1
A buffer solution is made up of a weak acid and its conjugate base. Show more…
Show all steps
Your feedback will help us improve your experience
Adi S and 76 other Chemistry 101 educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
How many buffering regions can be identified in the protonic equilibria of leucine?
Adi S.
The amino acid leucine has pKa values of 2.36 for the carboxylic acid group and 9.60 for the amino group. Images of alanine like that shown below are common on the internet. But, are they chemically accurate? A. Draw structures of leucine with the ionization states expected at pH values of 1, 7 and 11. (Draw a separate structure for each pH value). (3 points) B. Is there any pH at which the ionization state depicted in the image exists? Briefly explain why:
Calculate the isoionic and isoelectric pH of 0.01980 M leucine. Enter your answers to the hundredths place. Amino Acid pKa1 pKa2 Asparagine 2.16 8.73 Glutamine 2.19 9.00 Isoleucine 2.318 9.758 Leucine 2.328 9.744 Methionine 2.18 9.08 Phenylalanine 2.20 9.31 Proline 1.952 10.640 Serine 2.187 9.209 Tryptophan 2.37 9.33 Valine 2.286 9.719 isoionic pH = 6.038 isoelectric pH = 10.72
Recommended Textbooks
Chemistry: Structure and Properties
Chemistry The Central Science
Chemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD