or antibodies reacting to the body's own cells or 2. The disease causes neuromuscular junctions to not work properly, resulting in weakness. 3. In MS the myelin sheath of nerve fibers deteriorates, causing neuromuscular issues. 4. In CKD kidney disease and eventually death ensue. 5. In RA recurring inflammation in skeletal joints causes pain and a lack of mobility. 1. Autoimmune diseases are usually the result of either molecules.