2. Predict the stereochemistry of the major product in each of the following carbonyl addition reactions. a) O Ph PhMgBr ? b) O Ph OMe SPh NaBH4 ? c) O nBuMgBr ? O H O O
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The Grignard reagent acts as a nucleophile and attacks the carbonyl carbon, resulting in the formation of an alkoxide intermediate. The stereochemistry of the product will be determined by the attack of the nucleophile on the carbonyl carbon. Since the carbonyl Show more…
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