00:02
So from our question, we're looking and seeing that we're dealing with acetylcoa.
00:09
And so when it's in reference to the book, the textbook, and the chapter and what it talked about, it talked about acetylation, we know that acetylation is one of the types of modification that can be done during or post -transcriptional transcriptional modification that can occur to control gene regulation.
00:32
Or to regulate gene expression.
00:36
And typically when we acetylate a group, normally on the end terminal, we are actually turning on genes or activating genes to produce more product or protein.
00:52
So that's what this entire step is.
00:56
So this first molecule written out is lysine.
01:02
So this is a lysine in a histone tail.
01:09
And this is, i actually took this from the book.
01:13
And then this is our acetyl -coa.
01:17
So when we're acetylating our lysine residues, we're taking an acetyl group from our acetyl -coa.
01:31
So our question, now let's kind of look at the question.
01:34
So our question is asking us to come up with a way in which our acetyl co -ate or our acetyl group is transferred to this lysine residue.
01:53
So we know that we have a positive charge here and we've got these electrons here.
02:02
So oxygen has these electrons.
02:04
So what will happen is a nucleophilic attack will happen where our oxygen electrons will actually end up.
02:16
Well, this arrow is not pointing to the right thing, but we see that there's a positive charge...