Question

Why is the hydrolysis of an amide in aqueous acid an irreversible reaction? (Choose one) Me-C(=O)NH2 H3O+ / ? The amine leaving group is protonated. The carboxylic acid product is protonated. The amine leaving group is deprotonated. The carboxylic acid product is deprotonated. The amide carbonyl is protonated.

          Why is the hydrolysis of an amide in aqueous acid an irreversible reaction?
(Choose one)
Me-C(=O)NH2
H3O+ / ?
The amine leaving group is protonated.
The carboxylic acid product is protonated.
The amine leaving group is deprotonated.
The carboxylic acid product is deprotonated.
The amide carbonyl is protonated.

Why is the hydrolysis of an amide in aqueous acid an irreversible reaction?
(Choose one)
Me-C(=O)NH2
H3O+ / ?
The amine leaving group is protonated.
The carboxylic acid product is protonated.
The amine leaving group is deprotonated.
The carboxylic acid product is deprotonated.
The amide carbonyl is protonated.

Added by Zachary C.

Chemistry: Structure and Properties

Nivaldo Tro 2nd Edition

Instant Answer

Solved by Expert Arun Bana

10/29/2020

Step 1

The amide leaving group is protonated because it has Show more…

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Why is the hydrolysis of an amide in aqueous acid an irreversible reaction? (Choose one) Me-C(=O)NH2 H3O+ / Δ The amine leaving group is protonated. The carboxylic acid product is protonated. The amine leaving group is deprotonated. The carboxylic acid product is deprotonated. The amide carbonyl is protonated.