Question

Question 5 (1 point) Indicate the correct set of reactions from the choices below that would accomplish the following synthesis MOST efficiently (Hint: what is the MAJOR product of each step). target: OH OCH3 starting material: Br 1. DBU, 2. PhCO3H, 3. NaOCH3 then HCl 1. NaOCH3, low temp., 2. H2O2, 3. DMS 1. KOtBu, 2. OsO4, H2O2, H2O, 3. CH3OH 1. DBN, 2. MCPBA, 3. HCl (cat.), HOCH3 1. KOtBu, 2. Br2, CH3OH, H2O

          Question 5 (1 point)
Indicate the correct set of reactions from the choices below that would accomplish the following synthesis MOST efficiently (Hint: what is the MAJOR product of each step).
target: OH OCH3
starting material: Br
1. DBU, 2. PhCO3H, 3. NaOCH3 then HCl
1. NaOCH3, low temp., 2. H2O2, 3. DMS
1. KOtBu, 2. OsO4, H2O2, H2O, 3. CH3OH
1. DBN, 2. MCPBA, 3. HCl (cat.), HOCH3
1. KOtBu, 2. Br2, CH3OH, H2O

Question 5 (1 point)
Indicate the correct set of reactions from the choices below that would accomplish the following synthesis MOST efficiently (Hint: what is the MAJOR product of each step).
target: OH OCH3
starting material: Br
1. DBU, 2. PhCO3H, 3. NaOCH3 then HCl
1. NaOCH3, low temp., 2. H2O2, 3. DMS
1. KOtBu, 2. OsO4, H2O2, H2O, 3. CH3OH
1. DBN, 2. MCPBA, 3. HCl (cat.), HOCH3
1. KOtBu, 2. Br2, CH3OH, H2O

Added by Amy H.

Chemistry: Structure and Properties

Nivaldo Tro 2nd Edition

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Indicate the correct set of reactions from the choices below that would accomplish the following synthesis MOST efficiently (Hint: what is the MAJOR product of each step): 1. DBU, 2. PhCO3H, 3. NaOCH3 then HCl 1. NaOCH3, low temp., 2. H2O2, 3. DMS 1. KOtBu, 2. OsO4, H2O2, H2O, 3. CH3OH 1. DBN, 2. MCPBA, 3. HCl (cat.), HOCH3 1. KOtBu, 2. Br2, CH3OH, H2O