Predict the major product of the boxed reaction sequence. AlCl3 Zn(Hg) HCl heat ?? I II III (A) I (B) II (C) III (D) none Predict the major product of the below reaction sequence. HO OH 1. O3 H+ (cat.) 2. DMS 1. NaBH4, MeOH 2. H2SO4 (cat.) OH O O O HO OH HO OH I II III IV Identify the missing reagent required to complete the boxed transformation. Ph OH MeOH H2SO4 ?? Ph H NaBH4 LiAl(OtBu)3H H Al (DIBAH) LiAlH4 I II III IV
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- The first reaction sequence involves the reduction of a carbonyl group using Zn(Hg) and HCl, known as the Clemmensen reduction. This will reduce the carbonyl group to a methylene group. - The second step involves a Friedel-Crafts alkylation using AlCl3 and heat, Show more…
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