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1. LD50 is a measure of toxicity—lethal dose, 50 percent kill. LD50 is the dose in mg of the substance which is most likely to cause death within 14 days in one half of the animals used in the testing per kilogram of body weight. The LD50 of barium chloride is 118 mg/kg and the LD50 of strontium chloride is estimated at 2060 mg/kg. Which compound is more toxic? 2. Barium compounds are chemically very similar to strontium compounds. Water-soluble compounds of both are toxic, but to different degrees. An antidote for barium chloride poisoning is to orally administer 30 grams of sodium sulfate in 250 mL of water. Explain the chemical basis for this antidote.

          1. LD50 is a measure of toxicity—lethal dose, 50 percent kill. LD50 is the dose in mg of the substance which is most likely to cause death within 14 days in one half of the animals used in the testing per kilogram of body weight. The LD50 of barium chloride is 118 mg/kg and the LD50 of strontium chloride is estimated at 2060 mg/kg. Which compound is more toxic?
2. Barium compounds are chemically very similar to strontium compounds. Water-soluble compounds of both are toxic, but to different degrees. An antidote for barium chloride poisoning is to orally administer 30 grams of sodium sulfate in 250 mL of water. Explain the chemical basis for this antidote.

1. LD50 is a measure of toxicity—lethal dose, 50 percent kill. LD50 is the dose in mg of the substance which is most likely to cause death within 14 days in one half of the animals used in the testing per kilogram of body weight. The LD50 of barium chloride is 118 mg/kg and the LD50 of strontium chloride is estimated at 2060 mg/kg. Which compound is more toxic?
2. Barium compounds are chemically very similar to strontium compounds. Water-soluble compounds of both are toxic, but to different degrees. An antidote for barium chloride poisoning is to orally administer 30 grams of sodium sulfate in 250 mL of water. Explain the chemical basis for this antidote.

Added by Patrick J.

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