Reversible Oxidation of
a Secondary Alcohol to a Ketone
Many biochemical oxidation-reduction reactions
involve transfer of two electrons
In order to keep charges in balance, proton transfer
often accompanies electron transfer
In many dehydrogenases, the reaction proceeds by a
stepwise transfers of proton (H+) and hydride (:H-)
Lactate
lactate
dehydrogenase
Pyruvate