Select all of the reagents that can be used to remove the Fmoc protecting group from a peptide. Multiple select question. H2/Pd/C ammonia H2O/H+ piperidine trifluoroacetic acid
Added by Phillip M.
Step 1
The Fmoc (9-fluorenylmethoxycarbonyl) group is commonly used to protect the amino group of amino acids during peptide synthesis. To proceed with peptide synthesis, this protecting group must be removed. Show more…
Show all steps
Your feedback will help us improve your experience
Sri K and 96 other Chemistry 101 educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Which of the following reagents can be used to identify the N-terminal amino acid in peptide sequencing? PITC DCC FDNB FMOC
Sri K.
A peptide is synthesized using a solid-phase peptide synthesis strategy. Amino acids are typically protected using a Boc group, Fmoc group or Cbz group. Which amino acids will require two protecting groups? A G K M F
Madhur L.
What classes of reactions are involved in the cleavage of the Fmoc group with piperidine, leading to the unprotected amino acid and the fluorene by-product? Write mechanisms for these reactions.
Shaiju T.
Recommended Textbooks
Chemistry: Structure and Properties
Chemistry The Central Science
Chemistry
Transcript
600,000+
Students learning Chemistry with Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD
