00:01
Hello students, in this question we have been told that approximately 30 % of all college athletes are on some type of anabolic steroids.
00:16
So we have to discuss the biochemistry and physiology of this anabolic steroids.
00:31
So some of the questions on it is how do they work and how do they make muscles grow and do muscle cells undergo mitotic cell division and what is the connection with cholesterol, testosterone and estrogen.
01:05
What is the difference between anabolic steroids and the steroids doctors prescribe for inflammation? what is the problem with over -the -counter supplements such as androstenedime? what are the side effects of steroid use and do you think professional athletes should be tested for anabolic steroids? so firstly what are anabolic steroids? so they are synthetic version of the hormone testosterone which are normally produced in the body.
02:05
Testosterone is basically responsible for development of the male sexual characteristics such as muscle mass and strength.
02:20
So when anabolic steroids are taken they bind to the androgen receptor, androgen receptors in the muscle cell and so here what is happening is the muscle cells do not undergo mitosis like any normal cell.
02:50
What happens here is there is a growth in the muscle fiber.
02:58
Muscle fiber grows in size.
03:02
So that is what happens here.
03:04
That process is called as hypertrophy.
03:08
Instead of cells becoming more in the size of each cell becomes more larger.
03:18
So how are anabolic steroids connected to cholesterol, testosterone and estrogen? so cholesterol is the precursor for testosterone.
03:30
So to produce testosterone we need cholesterol in the body and anabolic steroid can increase the production of testosterone...