Question

Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2 - Tris or THAM] is a weak base frequently used to prepare buffers in biochemistry. Its Kb is 1.2 x 10^-6 and pKb is 5.92. The corresponding pKa is 8.08, which is near the pH of the physiological buffers, and so it exhibits good buffering capacity at physiological pH. What weight of THAM must be taken with 100 mL of 0.50 M HCl to prepare 1L of a pH 7.90 buffer? _______ g

Name: trishydroxymethylaminomethane hoch23cnh2 tris or tham is a weak base frequently used to prepare buffers in biochemistry its kb is 12 x 10 6 and pkb is 592 the corresponding pka is 808 which 24647
Uploaded: 2022-04-05T18:29:08-08:00
Duration: 3 min 24 s
Channel: David Collins
Description: trishydroxymethylaminomethane hoch23cnh2 tris or tham is a weak base frequently used to prepare buffers in biochemistry its kb is 12 x 10 6 and pkb is 592 the corresponding pka is 808 which 24647

          Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2 - Tris or THAM] is a weak base frequently used to prepare buffers in biochemistry. Its Kb is 1.2 x 10^-6 and pKb is 5.92. The corresponding pKa is 8.08, which is near the pH of the physiological buffers, and so it exhibits good buffering capacity at physiological pH. What weight of THAM must be taken with 100 mL of 0.50 M HCl to prepare 1L of a pH 7.90 buffer? _______ g

Added by Maria M.

Chemistry: Structure and Properties

Nivaldo Tro 2nd Edition

Instant Answer

Solved by Expert David Collins

04/05/2022

Step 1

First, we need to calculate the moles of HCl in 100 mL of 0.50 M HCl. The moles of HCl = Molarity x Volume(L) = 0.50 mol/L x 0.1 L = 0.05 mol. Show more…

Show all steps

Thanks for your feedback!

Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2 - Tris or THAM] is a weak base frequently used to prepare buffers in biochemistry. Its Kb is 1.2 x 10^-6 and pKb is 5.92. The corresponding pKa is 8.08, which is near the pH of the physiological buffers, and so it exhibits good buffering capacity at physiological pH. What weight of THAM must be taken with 100 mL of 0.50 M HCl to prepare 1L of a pH 7.90 buffer? _______ g