Question

Q3: Circle the most reactive nucleophile for SN2 reactions in the following sets of molecules. Tip: protic solvents form H-bonds with nucleophiles. Smaller nucleophiles form tighter packed solvation shells, reducing the nucleophilicity relative to larger nucleophiles. This trend is inverted in aprotic solvents due to the lack of H-bonding. Steric strain reduces nucleophilicity. a) In polar protic solvents: F? Cl? Br? I? b) In polar protic solvents: ?OH ?SH ?SeH c) In polar aprotic solvents: F? Cl? Br? I? d) In polar aprotic solvents: ?OH ?SH ?SeH

          Q3: Circle the most reactive nucleophile for SN2 reactions in the following sets of molecules.
Tip: protic solvents form H-bonds with nucleophiles. Smaller nucleophiles form tighter packed solvation shells, reducing the nucleophilicity relative to larger nucleophiles. This trend is inverted in aprotic solvents due to the lack of H-bonding. Steric strain reduces nucleophilicity.
a) In polar protic solvents: F? Cl? Br? I?
b) In polar protic solvents: ?OH ?SH ?SeH
c) In polar aprotic solvents: F? Cl? Br? I?
d) In polar aprotic solvents: ?OH ?SH ?SeH

Q3: Circle the most reactive nucleophile for SN2 reactions in the following sets of molecules.
Tip: protic solvents form H-bonds with nucleophiles. Smaller nucleophiles form tighter packed solvation shells, reducing the nucleophilicity relative to larger nucleophiles. This trend is inverted in aprotic solvents due to the lack of H-bonding. Steric strain reduces nucleophilicity.
a) In polar protic solvents: F? Cl? Br? I?
b) In polar protic solvents: ?OH ?SH ?SeH
c) In polar aprotic solvents: F? Cl? Br? I?
d) In polar aprotic solvents: ?OH ?SH ?SeH

Added by Daniel D.

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