What breeds have the higher odds of incontinence in male dogs?
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1. Progressive retinal atrophy (PRA) is an example of an autosomal recessive genetic disorder in dogs. In order to avoid creating offspring with PRA, dogs belonging to high-risk breeds should undergo genetic testing prior to breeding. a. A dog with PRA has what genotype? b. Can a dog with PRA have healthy parents (no PRA)? If so, what would be the genotype of each parent? What genetic term would describe these healthy parents? c. If 2 carriers for PRA mated, what is the probability of having puppies unaffected by PRA versus with PRA? Could there be a carrier for PRA within the litter of puppies? d. In order to decrease future incidence of PRA in breeding programs, dogs with which genotypes for PRA should be removed from the breeding program?
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Many dog breeds are susceptible to genetic diseases. For example, golden retrievers often have hip dysplasia and bull dogs often have respiratory problems. Discuss two ways in which centuries of dog breeding by humans may have led to these issues in dogs.
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Assume the mating of two dogs from different breeds that both show an excessive bleeding disorder. In one breed, the condition is an autosomal recessive and in the other a sex-linked recessive. The dogs used are an affected male Lab and an affected female Doberman. The progeny resulting from the mating are: All normal females, All affected males Which breed has the sex-linked disorder and what is the genotype for that breed at both loci?
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