Nester's Microbiology: A Human Perspective

Denise Anderson, Sarah Salm, Deborah Allen

Chapter 20

Antimicrobial Medications - all with Video Answers

Educators

Chapter Questions

Problem 1

Which of the following targets would you expect to be the most selective with respect to toxicity?
a) Cytoplasmic membrane function
b) DNA synthesis
c) Glycolysis
d) Peptidoglycan synthesis
e) $70 \mathrm{S}$ ribosome

Joanna Quigley

Joanna Quigley

Numerade Educator

Problem 2

Penicillin has been modified to make derivatives that differ in all of the following except
a) spectrum of activity.
b) resistance to $\beta$ -lactamases.
c) potential for allergic reactions.
d) a and c.

Joanna Quigley

Numerade Educator

Problem 3

Which of the following is the target of $\beta$ -lactam antibiotics?
a) Peptidoglycan synthesis
b) DNA synthesis
c) RNA synthesis
d) Protein synthesis
e) Folic acid synthesis

Joanna Quigley

Numerade Educator

Problem 4

Which of the following statements is false?
a) A bacteriostatic chemical stops the growth of a microorganism.
b) The lower the therapeutic index, the less toxic the medication.
c) Broad-spectrum antibiotics are associated with the development of severe Clostridium difficile infections.
d) Azithromycin has a longer half-life than does penicillin V.
e) Chloramphenicol can cause a life-threatening type of anemia.

Joanna Quigley

Numerade Educator

Problem 5

All of the following interfere with the function of the ribo-
some except
a) fluoroquinolones.
b) lincosamides.
c) macrolides.
d) streptogramins.
e) tetracyclines.

Joanna Quigley

Numerade Educator

Problem 6

The target of the sulfonamides is
a) cytoplasmic membrane proteins.
b) folate synthesis.
c) gyrase.
d) peptidoglycan biosynthesis.
e) RNA polymerase.

Joanna Quigley

Numerade Educator

Problem 7

Routine antimicrobial therapy to treat tuberculosis involves taking
a) one medication for 10 days.
b) two or more medications for 10 days.
c) one medication for at least 6 months.
d) two or more medications for at least 6 months.
e) five medications for 2 years.

Joanna Quigley

Numerade Educator

Problem 8

Staphylococcus aureus strains referred to as HA-MRSA are sensitive to
a) methicillin.
b) penicillin.
c) most cephalosporins.
d) vancomycin.
e) none of the above.

Joanna Quigley

Numerade Educator

Problem 9

Acyclovir is a
a) nucleoside analog.
b) non-nucleoside polymerase inhibitor.
c) protease inhibitor.
d) none of the above.

Joanna Quigley

Numerade Educator

Problem 10

The antifungal medication griseofulvin is used to treat
a) vaginal infections. $\quad$ b) systemic infections.
c) nail infections.
d) eye infections.

Joanna Quigley

Numerade Educator