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Abrams' clinical drug therapy : rationales for nursing practice

Geralyn Frandsen; Sandra Smith Pennington; Anne Collins Abrams

Chapter 19

Drug Therapy With Macrolides, Ketolides, and Miscellaneous Anti-Infective Agents - all with Video Answers

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Chapter Questions

01:44

Problem 1

A 47-year-old woman with bipolar disorder is admitted to a hospital with a diagnosis of a vancomycin-resistant skin infection. She is taking lithium carbonate $300 \mathrm{mg}$ orally three times per day. The medical intern orders linezolid $600 \mathrm{mg}$ intravenously every 12 hours for 14 days.
- What is problematic about the use of linezolid and lithium carbonate?
- What is the action of linezolid (Zyvox)?
- What central nervous system adverse effects does the nurse need to assess for?
- Can the patient safely receive any other medications to treat her bipolar disorder?
- How is intravenous (IV) linezolid (Zyvox) administered?

Akhil Choudhary
Akhil Choudhary
Numerade Educator

Problem 2

A 38-year-old man sustained a construction-related injury 2 weeks ago. The wound site is reddened and draining. He is admitted to an infection control unit and placed on wound precautions. After obtaining a culture and sensitivity, a physician prescribes quinupristin-dalfopristin $7.5 \mathrm{mg}$ per $\mathrm{kg}$ intravenously every 12 hours for 7 days.
- What organisms does quinupristin-dalfopristin effectively treat?
- The patient complains of severe venous irritation during the administration of the first dose. What action should the nurse take to prevent this discomfort with future infusions?
- Which IV fluid does the nurse use for quinupristin-dalfopristin administration?
- It is necessary to infuse quinupristin-dalfopristin for what length of time?
- The patient develops gastroesophageal reflux. An intern orders IV metoclopramide. What precaution does the nurse need to take in administering these two IV medications?

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