Chapter 11, Drugs That Affect the Immune System Video Solutions, Understanding Pharmacology: Essentials for Medication Safety

Problem 1

What does a sensitized B cell produce when it is stimulated with exposure to a foreign invader?
A. Antigen
B. Antibody
C. Vaccine
D. Toxin

Sam Limsuwannarot

Numerade Educator

00:29

Problem 2

What type of white blood cell (leukocyte) provides true immunity?
A. Eosinophil
B. Lymphocyte
C. Macrophage
D. Neutrophil

Anna Miller

Numerade Educator

Which statement about artificially acquired passive immunity is true?
A. It can be transferred from one person to another.
B. It is the longest-lasting type of immunity.
C. It requires "boosting" on a regular schedule.
D. It is present in adults but not in children or teenagers.

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01:04

Problem 4

Which vaccination uses a toxoid rather than a killed vaccine or an attenuated vaccine to stimulate immunity?
A. Polio
B. Measles
C. Tetanus
D. Hepatitis A

Joanna Quigley

Numerade Educator

00:54

Problem 5

What is the desired response of successful vaccination?
A. Inactivation of dangerous toxoids produced by certain diseasecausing viruses
B. Immunization with immune resistance to the substance in the vaccine
C. B cells convert to $\mathrm{T}$ cells that are better able to recognize invading microorganisms
D. Development of generalized protective inflammatory responses and innate immunity

Grant Castaneda

Numerade Educator

03:22

Problem 6

Which antirejection drug belongs to the calcineurin inhibitor class?
A. Azathioprine (Imuran)
B. Basiliximab (Simulect)
C. Cortisol (Prednisone)
D. Tacrolimus (Prograf)

Bryan Valdivia

Numerade Educator

01:09

Problem 7

What category of selective immunosuppressant drugs is most likely to trigger a severe allergic reaction or anaphylaxis?
A. Antiproliferatives
B. Calcineurin inhibitors
C. Monoclonal antibodies
D. Polyclonal antibodies

Courtney Burson

Numerade Educator

01:56

Problem 8

What is the immunologic outcome of autoimmune disease?
A. The person is more at risk for infection.
B. The person is a risk for tissue damage from inappropriate immune responses.
C. The person is unlikely to develop a fever even when serious infection is present.
D. The person will be unable to generate specific antibodies in response to a vaccination.

Joanna Quigley

Numerade Educator

01:59

Problem 9

A 75-year-old woman tells you that she is afraid she will get shingles if she visits her older sister who has shingles. What is your best response?
A. "You can only get shingles from the virus left in your body from when you had the chickenpox."
B. "Shingles and chickenpox are caused by the same virus. So if you have already had chickenpox, you are immune to shingles."
C. "Yes, shingles is a highly contagious disease and is easily transmitted from one person to another by air droplets."
D. "Have you ever had shingles? Because once you have shingles, you will never get sick with it again."

Grant Castaneda

Numerade Educator

00:45

Problem 10

A patient who has many serious health problems has just been exposed heavily to hepatitis B. Because this person may not survive an infection at this time, he is given human immunoglobulin with a high concentration of antihepatitis antibodies. What type of immunity will result from this intervention?
A. Artificially acquired active immunity
B. Artificially acquired passive immunity
C. Naturally acquired active immunity
D. Naturally acquired passive immunity

Chinwe Abaraoha

Numerade Educator

03:07

Problem 11

Why is antibody-mediated immunity considered to be a type of "adaptive" immunity?
A. The immune system adapts to the presence of specific invaders or antigens by making specific antibodies against those invaders or antigens.
B. The antibody-making cells are more resistant to environmental attacks on the immune system than are the cells involved in innate immunity.
C. The immune system is able to adapt to the severity of infection by matching the number of neutrophils and other white blood cells generated with the number of organisms causing the infection.
D. After childhood, the immune system adapts the rate of leukocyte production with the rate of leukocyte destruction to maintain a "steady-state" or constant number of white blood cells for maximum infection protection.

Justin Im

Numerade Educator

03:07

Problem 12

Why does artificially acquired passive immunity have such a short duration of effectiveness?
A. Because antibodies are made of protein, they are digested and excreted by the intestinal tract within a week to 10 days.
B. Antibodies made by another person or animal are viewed as a foreign invader by the recipient's immune system.
C. This type of immunity requires constant "boosting" to maintain normal levels of antibody production.
D. It can be easily overwhelmed when invading microorganisms reproduce rapidly.

Justin Im

Numerade Educator

01:21

Problem 13

Which mother should receive RhoGAM?
A. An Rh-positive mother who just delivered an Rh-negative infant
B. An Rh-positive mother who just delivered an Rh-positive infant
C. An Rh-negative mother who just delivered an Rh-negative infant
D. An Rh-negative mother who just delivered an Rh-positive infant

Rithvik Manne

Numerade Educator

Problem 14

Which immunizations are recommended for pregnant women to receive during each pregnancy? Select all that apply.
A. Diphtheria
B. Hepatitis B
C. Human papilloma virus
D. Pertussis
E. Polio
F. Measles
G. Seasonal influenza
H. Tetanus

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01:24

Problem 15

The patient who received basiliximab (Simulect) just before and on the fourth day after his kidney transplant asks how long he will have to take the prescribed oral mycophenolate (CellCept). What is your best response?
A. "Because acute rejection is most common during the first 12 weeks after transplantation, you can stop the drug after 3 months."
B. "We will monitor your white blood cell count and when lymphocytes remain lower than normal for a year, we will discontinue the drug."
C. "Because you will be at an increased risk for infection, you will need to continue taking this drug for the rest of your life."
D. "Because this drug prevents rejection, you will need to take the drug as long as the new kidney continues to function."

Joanna Quigley

Numerade Educator

01:23

Problem 16

A patient is prescribed a daily dose of azathioprine (Imuran) of $2 \mathrm{mg} / \mathrm{kg}$ orally daily. The patient weighs $165 \mathrm{lb}$.
What is the patient's weight in $\mathrm{kg}$ ?_________
What is the correct dose?_____________
The drug is available in a $\overline{50-\mathrm{mg}}$ scored tablet. How many tablets will you give?_____________

Heather Zimmers

Numerade Educator

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