Which of the following statements about botulism is true?
a) It is caused by Bacillus botulinum, an obligate aerobe.
b) The toxin is heat-resistant, withstanding temperatures of $100^{\circ} \mathrm{C}$
c) The organism that causes botulism can cause disease without encountering the immune response.
d) Vaccinations are routinely given to prevent botulism.
e) Symptoms of botulism include uncontrolled contraction of muscles.