Batch processes are often used in chemical and pharmaceutical operations to achieve a desired chemical composition for the final product. Related heat transfer processes are typically transient, involving a liquid of fixed volume that may be heated from room temperature to a desired process temperature, or cooled from the process temperature to room temperature. Consider a batch process for which a pharmaceutical (the cold fluid, $c$ ) is poured into an insulated, highly agitated vessel (a stirred reactor) and heated by passing a hot fluid ( $h$ ) through a submerged heat exchanger coil of thinwalled tubing and surface area $A_{s}$. The flow rate, $\dot{m}_{h}$, mean inlet temperature, $T_{h i}$, and specific heat, $c_{p, h}$, of the hot fluid are known, as are the initial temperature, $T_{c, i}<T_{h, i}$, the volume, $V_{c}$, mass density, $\rho_{c}$, and specific heat, $c_{v, c}$, of the pharmaceutical. Heat transfer from the hot fluid to the pharmaceutical is governed by an overall heat transfer coefficient $U$.
(a) Starting from basic principles, derive expressions that can be used to determine the variation of $T_{c}$ and $T_{h, o}$ with time during the heating process. Hint: Two equations may be written for the rate of heat transfer, $q(t)$, to the pharmaceutical, one based on the logmean temperature difference and the other on an energy balance for flow of the hot fluid through the tube. Equate these expressions to determine $T_{\text {ho }}(t)$ as a function of $T_{c}(t)$ and prescribed parameters. Use the expression for $T_{h, o}(t)$ and the energy balance for flow through the tube with an energy balance for a control volume containing the pharmaceutical to obtain an expression for $T_{c}(t)$.
(b) Consider a pharmaceutical of volume $V_{c}=1 \mathrm{~m}^{3}$, density $\rho_{c}=1100 \mathrm{~kg} / \mathrm{m}^{3}$, specific heat $c_{v, c}=2000 \mathrm{~J} / \mathrm{kg} \cdot \mathrm{K}$, and an initial temperature of $T_{c i}=25^{\circ} \mathrm{C}$. A coiled tube of length $L=40 \mathrm{~m}$, diameter $D=50 \mathrm{~mm}$, and coil diameter $C=500 \mathrm{~mm}$ is submerged in the vessel, and hot fluid enters the tubing at $T_{h, i}=200^{\circ} \mathrm{C}$ and $\dot{m}_{h}=2.4 \mathrm{~kg} / \mathrm{s}$. The convection coefficient at the outer surface of the tubing may be approximated as $h_{o}=1000 \mathrm{~W} / \mathrm{m}^{2} \cdot \mathrm{K}$, and the fluid properties are $c_{p, h}=2500 \mathrm{~J} / \mathrm{kg} \cdot \mathrm{K}, \mu_{\mathrm{h}}=0.002 \mathrm{~N}+\mathrm{s} / \mathrm{m}^{2}, k_{h}=$ $0.260 \mathrm{~W} / \mathrm{m} \cdot \mathrm{K}$, and $P r_{\mathrm{h}}=20$. For the foregoing conditions, compute and plot the pharmaceutical temperature $T_{c}$ and the outlet temperature $T_{h o o}$ as a function of time over the range $0 \leq t \leq 3600 \mathrm{~s}$. How long does it take to reach a batch temperature of $T_{c}=160^{\circ} \mathrm{C}$ ? The process operator may control the heating time by varying $\dot{m}_{h b}$. For $1 \leq \dot{m}_{h} \leq 5$ $\mathrm{kg} / \mathrm{s}$, explore the effect of the flow rate on the time $t_{c}$ required to reach a value of $T_{c}=160^{\circ} \mathrm{C}$.