Some amount of circulating cholesterol is absorbed from dietary sources. This absorption requires the bile acids to solubilize the cholesterol in the gut so it can be absorbed. Cholestyramine is an ionexchange resin that binds bile acids and therefore interferes with the enterohepatic circulation. Since bile acids are necessary for dietary cholesterol absorption, and also are the main sink for cholesterol in the body, ingesting cholestyramine should lower blood cholesterol. Do you anticipate any negative side effects of cholestyramine ingestion?