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# In chemistry, uncertainty is the expected error in a measurement, which is the difference between the value of a measured quantity and the value of the quantity as determined by the measurement process. Uncertainty is usually expressed in terms of standard deviation. Uncertainty can be quantified in several ways: for example, by using statistical methods, or by analyzing the variance of the individual measurements. The term "uncertainty" is also used in science and engineering in a broader sense, to indicate the lack of knowledge of either the value of a quantity or even its existence.

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