Drug Monographs
What is a drug monograph?
How do I create a drug monograph?
Background Information
Natural progression - Current standard of care
> PK/PD : Operations Cost
Background Information: Drug
Background Information: Operations
Background Information: Cost
Identify Potentially Useful Evidence
:Dates of searches - Search yield Number of relevant studies selected for further review
. Webinars : Templates : Checklists : Resources for researching a formulary request
- Manufacturer's Press Release/Investor Relations
UpToDate/Dynamed
Lexicomp Clinical Pharmacology Micromedex
Purple Book The Yellow Book Drug topics Red Book
Critically Appraise and Summarize the Evidence: Citation
: Study size Purpose
Exclusion criteria Primary endpoint :Secondary endpoint Definitions Treatment groups
:Secondary endpoint Adverse effects Limitations Conclusion
Create an Overall Summary
of patients (n, general age,_% women/men). The next sentence should explicitly state 'the primary outcome of - in -% of Drug A patients versus - - % of other group (p=
included ---. (%). State if the medication has a REMS program and why
medication has shown efficacy in. One sentence about who is requesting and who is planning to use. One sentence, without biased statements, about comparative efficacy to other treatments (if they exist) or efficacy in specific patient populations. One sentence about cost to the organization.
Rec