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Organic Chemistry I - Acids and Bases

LET'SGET STARTED Chapter 3: Acids and Bases What's Covered? Types of Acids/Bases Identify Conjugate acid/bases Draw Acid/Base mechanisms Determine products and equilibrium Use pKa Values WATCH THE VIDEO TAKENOTES .DOPRACTICE PROBLEMS BEANACTIVE LEARNER hdlocuoeotes Types of Acids/Bases: Bronsted-Lowry definition Acids donate a proton,H Basesacceptaproton Alss Lewis Acio HO 5- :15: H H Acid Base conjugate (proton donor) (proton acceptor) conjugate (base acidy Lewis acid/base definition A Lewis acid accepts a pair of electrons - A Lewis base donates a pair of electrons B H Base 1 Curved Arrows in Acid/Base Reactions What is an acid/base mechanism? ae ie Thebaseattacksthe acidtusing a pair of electrons Nat The acid cannot lose its proton without the base taking it. All charges should be balanced in the reaction, a + charge with a -- charge to form a B neutral solution. H i5 NOf StaY bY you8sclF Watch out for spectator ions (NatMg*2,CI-etc) The acid/base mechanism shows two arrows indicatingthat two pairs of electrons move A: simultaneously Electrophile: Acid get Atached Electron loving, gets attacked Electron Poor, empty orbital, &+ or + charge V-H3 Nucleophile:Base Seeking positive, attacks with 2 electrons Electron Rich, - or - charge H H Curved Arrows in Acid/Base Reactions: Example: H Base HOH Acid conjugate base conjugate (proton donor) (proton acceptor) Try it On Your Own! Draw the curved arrow mechanism. Label the acid, base, conjugate acid and conjugate base. HO:0 Conj. Base H .O. Base Consi Acid Acid 2. Curved Arrows in Acid/Base Reactions: AnswerTry it On Your Ownl Draw the curved arrow mechanism. Label the acid, base, conjugate acid and conjugate base H O. :0H Cms. Base Acid Gms. acid bast -In the above reaction how willing was water to give up its proton? .How stable is the conjugate base? .Which side of the equilibrium is favored? Quantifying Acidity and Basicity: pKa values range from -10 to 50. Lower pka=stronger acid The stronger an acid the weaker its conjugate base. VeaY Acidic % i. [OWexIKa- S+tongex cucid L.P.S.A 8 YAcid X X. less Stabl