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Pharmacology and Patient Assessment in CNS Depressants

Action Uses Interactions/co ntraindications - Other CNS depressants - Alcohol Contraindications Side effects/Adverse reactions - How to memory recognize - impairment, how to prevent - Depression, tolerance and dependence hypotension - Pre-assessment (what do I need to know before I give it?) Interventions including Benzodiazepines Alprazolam Lorazepam Diazepam Midazolam Interacts with neurotransmitter GABA to reduce neuron excitability Reduce anxiety and insomnia Pre-op sedation, alcohol/substance withdrawal, antiseizure drug Interaction - Respiratory depression - allergy - Lethargy, drowsiness, confusion, Caution - older adults - depression, suicidal ideation - sever liver and kidney problems Assessment - determine whether the patient has a history of insomnia or anxiety disorders. - Review drug history and medical history Assess patients mental status - - Vital signs - Monitor vital signs Created T. Campos, MSN, RN, CNE 4/2018, revised 6/2019 - tcampos@galencollege.edu teaching Therapeutic response Action/use - Teach to use nonpharmacologi cal methods to induce sleep - Observe patien for adverse reactions especially in older - Adverse patient to report adverse reactions,such as respiratory depression, feeling of depression. - Teach patients that these drugs should be gradually withdrawn. Not to be stopped abruptly. Zolpidem Sumatript an - Neurotrans mitter inhibition, C NS depression - Duration of action is 6- 8hrs Use - Treat short term insomnia( le ss than 10 days) Smaller doses for older adults - Lidocaine Spinal/epidural anesthesia Anti-gout - Allopurinol Classification Contraindication Non- benzodiazepines - Allergy to Created T. Campos, MSN, RN, CNE 4/2018, revised 6/2019 - tcampos@galencollege.edu s/ Interactions Side effects/Adverse reactions - how to prevent - how recognize Pre-assessment (What do I need to know before I give it) Interventions including teaching benzodiazep ines - Respiratory depression - Liver and renal disease - Children/old er adults Interactions - Other cns depressants - Alcohol Food - decreases absorption - Drowsiness - Lethargy - Dizzy - Memory impairment Adverse reactions - Residual drowsiness( hangover) Vivid - dreams, nightmares, drug dependence drug tolerance, excessive depression, respiratory depression, hypersensiti vity - Vital signs - Possible reason for sleep disturbances - Drug and medical hisotry Interventions - Monitor vs and LOC - Observe for side Created T. Campos, MSN, RN, CNE 4/2018, revised 6/2019 - tcampos@galencollege.edu