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Principles of Epidemiology and Salmonella Outbreak

Amber McAllister Principles of Epidemiology Anne McHugh August 14, 2022 Final Project Salmonellosis, more commonly known as Salmonella, is a gastrointestinal illness caused by bacteria. The symptoms can include sudden onset of headache, abdominal pain, diarrhea (which may be bloody), nausea, and sometimes vomiting. Fever is almost always present. The illness typically lasts for 5-7 days and usually does not require treatment unless the patient becomes severely dehydrated or the infection spreads from the intestines. In the immunocompromised host or an overwhelming infection in a normal host, Salmonella may spread to the blood stream and other body sites, and can cause death unless treated promptly with antibiotics. (Stehr-Green, 2016) The bacteria live in the intestinal tracts of their hosts which can be humans or animals. It can be transmitted to humans by eating foods that are contaminated with animal fecal matter. Some of the risk factors in transmitting the bacteria are improper hand washing while handling raw meats and eggs or after using the restroom. However, studies have shown that the number one risk factor for humans is the consumption of raw or undercooked eggs. This has been proven in the case study provided, by researching eggs and where they came from. and how they were handled prior to consumption. It was found that non-sanitized eggs that were consumed from unsanitary farms were more likely to contract Salmonella. Table 1 from the case study, it is shown from 1995-97, 257 laboratory-confirmed cases of S. Enteritidis infection were reported in Trinidad and Tobago. In those years approximately, 86 cases were reported each year for an annual incidence of 6.8 per 100,000 people in the population. In general, the geographic distribution of patients with S. Enteritidis infection reflected population distributions on the two islands. The largest numbers of cases were reported from the most populous counties of St. George and Victoria. An average of 4 people died each year from salmonella infection. (Stehr- Green, 2016) Breaking this information down to just formulas would be equal to: Incidence Rate= (86 cases/1,265,000population) *100,000= 6.79, rounded to 6.8 Prevalence= (1097cases in study/1,265,000 population) = 86.7 per 100,000 people Morality = (40/ 1,265,000) * 100,000= 3.16, rounded to 4 In table 2 of the case study, the odds ratio can be determined as the highest at 18.9 being raw or undercooked eggs and the lowest at 0.03 for refrigerated eggs at home. There were some other odds being factored in such as shells being eaten coming in at 8.8 which is the second highest odd therefore supporting the case study that the common exposure to unsanitary eggs was the leading cause of the Salmonella outbreak. An odds ratio (OR) is another measure of association that quantifies the relationship between an exposure with two categories and health outcome. Referring to the four cells in Table 3.15, the odds ratio is calculated as Odds ratio= (a/b)(c/d)= ad/bc where a = number of persons exposed and with disease b = number of persons exposed but without disease c