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Introduction to Cell Transport

protlins change Diffusien within cells and hiosuls Acro3s jayys of one or two cell ,diffusion i5 rapidenary9 Difhusion across membraunes Moiecules diffuse to Hurough the membrane thaf Hhey arl Permauble to bo nlach aquilibrium,wherv their motlment bond enery) onlenercy) voypyuayxQn YI nhuny2 ynu Ou u} Hn63r Simple diffusion talis plar through the phospholipid bilayu Smal unchargid moleailes can pass through easily bonds-in solukon 6.4 Achive Transport acr0ss Membranes Requires Enargy -Actiu transpont: movement of mdicules or ions against a gradient hhmn fo qmdun rm sonhr? ATP Act've trangport is direch'onal Dituston : inoue in eiHer direchon just nd fo be down theic concnlthe Active transport iVinchonaly move ciRur inps oc out There ace 3 iinds : unipbrter : sinyle substane in ane diach'on couplid trusporters L anHipodens Hwo substounu in dfftrent opposite direchons Different enengy sourus dihinguish different achivetransport syshems & bas ic typis of achive transport: + Pnimary achive tanspont: diract hydolysis of ATP- givs energy requiced for transport. + Secondany achiva franspont (co treunspont); energy is fom ion conontiahon gradient establishec usiney A pnmany active transpo Hgdrotysi3 of A7P-7 ADP Pi i fATP t_3Na+ biad to pumP 7 H ycV01ysis ATP~ ADP rPi 7Coeate 9ihe hor &L to biad Vigitalis, Ouabain , Weak deart contradion of keart muscfe. tronsport into cell It use ialo'muhon fom IKr int onvi'onmint lo conhol, requlalx phuy>io(og) iVervous system are inlormghion syshem and hehavibr of organ' m - Porsible du la properHe3 cf aeuon3 Varfxbratu) alro hewe glia ay (eir adihonal alrVe c