LECTURE: CONNECTIVE TISSUE DISORDERS WEEK: 1 RHEUMATIC HEART DISEASE (RHD) A disease connected to those in poverty or with a low economic disadvantage and is disproportionally overrepresented in the indigenous Australian population occurs in children aged 5-15. Affects the Functioning of heart values due to nodules developing prevent efficient closing CAUSES A consequence of streptococcus sp. An infection of the pharynx (pharyngitis) Leads to rheumatic Fever Genetic susceptibility plays a role A B CLINICAL MANIFESTATIONS Most cases are diagnosed with an ECG Heart murmur (common sign) Chest pain More severe disease presents with tymphocytes Artstrep Breathlessness on exertion Blood voscel Breathlessness on lying down (orthopnoea) Weakness & tiredness ACUTE AREUMATIC HEART DISEASE CROSS-REACTIONS Swelling of the legs (peripheral oedema) Vapetalora CONSEQUENCES Myncarda: Aschoff body 6 Devier 2005 Fibanous porficardos Can lead to rheumatic carditis which can affect any / all layers of the heart Epicardium, myocardium, endocardium or values Heart Failure Can lead to infective endocarditis MANAGEMENT Management of RHD depends on: Heart valve /s that have been affected Severity of disease Management Focuses on: Reducing symptoms Preventing complications through anti- microbial therapy